Jacques H. van Boom (1937-2004)
Simpelveld, The Netherlands
The 'van Boom's phosphotriester modification' which made it possible to synthesise DNA fragments both on a large scale and in an automated, solid support fashion. Discoveries included the first single atom structure of a defined DNA duplex and a new type of duplex DNA (Z-DNA).
Researcher in Leiden
Today in Leiden
The Leiden Institute of Chemistry boasts more than 60 PhD and numerous post-doc students supervised by Boom. He has also brought greater national and international prominence to the Institute, being one of the most influential Dutch scientists of the last 25 years.